Are people with autoimmune disease more likely to have COVID-19?
A study by researchers at the University of Toronto, in collaboration with CITF-funded researcher Dr. Sasha Bernatsky from the Research Institute of the McGill University Health Centre, observed that people with autoimmune diseases had the same proportion of SARS-CoV-2 positive tests and a similar disease incidence compared to the general population in 2020.
Increasing evidence regarding antibodies in saliva following COVID-19 infection or vaccination
Individuals who have recovered from COVID-19 or who have received SARS-CoV-2 vaccines (mRNA or adenovirus-based) have been shown to have virus-neutralizing activity in their saliva.
Mental illness and substance use also linked to increased risk of hospitalization
In a preprint that has not been peer-reviewed, CITF Leadership Group member Dr. Mel Krajden and colleagues sought to identify factors associated with COVID-19 hospitalization by looking at all individuals with lab-confirmed SARS-CoV-2 in British Columbia as of January 15, 2021.
The need to improve vaccine messaging and outreach: COVID-19 vaccine intention among women and gender-diverse individuals living with HIV in British Columbia
In their recent pre-print, not yet peer-reviewed, CITF Leadership Group member Dr. Gina Ogilvie, VSRG Working Group member Dr. Manish Sadarangani and colleagues in British Columbia explored COVID-19 vaccination intention among women and gender diverse individuals living with HIV.
Newly discovered rogue antibodies: why some older adults are at higher risk of severe COVID-19 illness
A collaborative effort of over 150 scientists from over 20 countries, including CITF-funded researcher Dr. Donald Vinh from McGill University Health Centre and the Research Institute of the McGill University Health Centre, has led to the identification of a surprisingly high prevalence of a type of antibody that has been linked to fatal outcomes of COVID-19.
Males aged between 10-49 years are an underrecognized group at high risk for SARS-CoV-2 infection
In a publication led by Dr. David Fisman from the University of Toronto in the Annals of Internal Medicine, CITF-funded researcher Dr. Sheila O’Brien and CITF Testing Working Party member Dr. Steven Drews, both from Canadian Blood Services, worked with colleagues from the University of Toronto and the University of Guelph and found that when accounting for testing rates, younger people in Ontario contracted SARS-CoV-2 more frequently than older people.
Hospitalization trends and death rates among Ontario’s nursing home residents in 2020
Investigators from the Canadian Immunization Research Network (CIRN), including CITF-funded researchers Drs. Jeffrey Kwong and Kumanan Wilson, provided epidemiological baseline rates of mortality and hospitalization to study COVID-19 outcomes in nursing home residents in Ontario.
COVID-19 vaccine immunogenicity in people living with HIV-1
Few studies have shown that immunocompromised individuals may mount attenuated antibody responses, compared to their otherwise healthy counterparts.
Duration of protection and effectiveness of a Quebec developed vaccine against SARS-Co-V2
Along with colleagues, CITF Scientific Advisor Dr. Matthew Cheng and CITF-funded researcher Dr. Donald Vinh from McGill University and the RI-MUHC, have been studying the effectiveness and immunogenicity of the Made-in-Quebec, plant-based Medicago vaccine.